Identification of the high-affinity tolbutamide site on the SUR1 subunit of the K(ATP) channel.
ATP-sensitive potassium channels (K(ATP)) are formed from four pore-forming Kir6.2 subunits complexed with four regulatory sulfonylurea receptor subunits (SUR1 in pancreatic beta-cells, SUR2A in heart). The sensitivity of the channel to different sulfonylureas depends on the SUR isoform. In particul...
Những tác giả chính: | Ashfield, R, Gribble, F, Ashcroft, S, Ashcroft, F |
---|---|
Định dạng: | Journal article |
Ngôn ngữ: | English |
Được phát hành: |
1999
|
Những quyển sách tương tự
-
Identification of the high affinity tolbutamide site on the SUR1 subunit of the K-ATP channel
Bằng: Gribble, F, et al.
Được phát hành: (1999) -
Interactions between tolbutamide and nucleotides on cloned K-ATP channels.
Bằng: Gribble, F, et al.
Được phát hành: (1997) -
The interaction of nucleotides with the tolbutamide block of cloned ATP-sensitive K+ channel currents expressed in Xenopus oocytes: a reinterpretation.
Bằng: Gribble, F, et al.
Được phát hành: (1997) -
TOLBUTAMIDE, AN INHIBITOR OF ATP-SENSITIVE K-CHANNELS, EXCITES CAROTID-BODY CHEMORECEPTORS IN THE CAT
Bằng: Ashcroft, F, et al.
Được phát hành: (1987) -
The ATP- and tolbutamide-sensitivity of the ATP-sensitive K-channel from human pancreatic B cells.
Bằng: Ashcroft, F, et al.
Được phát hành: (1989)