Identification of the high-affinity tolbutamide site on the SUR1 subunit of the K(ATP) channel.
ATP-sensitive potassium channels (K(ATP)) are formed from four pore-forming Kir6.2 subunits complexed with four regulatory sulfonylurea receptor subunits (SUR1 in pancreatic beta-cells, SUR2A in heart). The sensitivity of the channel to different sulfonylureas depends on the SUR isoform. In particul...
| Hlavní autoři: | , , , |
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| Médium: | Journal article |
| Jazyk: | English |
| Vydáno: |
1999
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Identification of the high affinity tolbutamide site on the SUR1 subunit of the K-ATP channel
Vydáno 1999
Journal article