Gene expression profiling of erythroblasts from refractory anaemia with ring sideroblasts (RARS) and effects of G-CSF.

Refractory anaemia with ring sideroblasts (RARS) is characterized by anaemia, erythroid apoptosis, cytochrome c release and mitochondrial ferritin accumulation. Granulocyte-colony-stimulating factor (G-CSF) inhibits the first three of these features in vitro and in vivo. To dissect the molecular mec...

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Bibliographic Details
Main Authors: Nikpour, M, Pellagatti, A, Liu, A, Karimi, M, Malcovati, L, Gogvadze, V, Forsblom, A, Wainscoat, J, Cazzola, M, Zhivotovsky, B, Grandien, A, Boultwood, J, Hellström-Lindberg, E
Format: Journal article
Language:English
Published: 2010