Tryptophan degradation by human placental indoleamine 2,3-dioxygenase regulates lymphocyte proliferation.

1. The physiological importance of human placental indoleamine 2,3-dioxygenase (EC 1.13.11.42), the first and rate-limiting enzyme in tryptophan metabolism, in regulating feto-maternal immunology has been studied. 2. Concentrations were measured in placental villous explant conditioned media of 14 a...

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Bibliographic Details
Main Authors: Kudo, Y, Boyd, C, Sargent, I, Redman, C
Format: Journal article
Language:English
Published: 2001