Spironolactone to prevent cardiovascular events in early-stage chronic kidney disease (STOP-CKD): Study protocol for a randomized controlled pilot trial

Background: Chronic kidney disease is associated with increased arterial stiffness even in the early stages and this is thought to be a key mediator in the pathophysiology of the increased cardiovascular risk associated with this condition. The use of low-dose spironolactone has previously been show...

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Bibliographic Details
Main Authors: Ng, K, Jain, P, Heer, G, Redman, V, Chagoury, O, Dowswell, G, Greenfield, S, Freemantle, N, Townend, J, Gill, P, McManus, R, Ferro, C
Format: Journal article
Language:English
Published: BioMed Central 2014