p62 filaments capture and present ubiquitinated cargos for autophagy

p62 filaments capture and present ubiquitinated cargos for autophagy

The removal of misfolded, ubiquitinated proteins is an essential part of the protein quality control. The ubiquitin‐proteasome system (UPS) and autophagy are two interconnected pathways that mediate the degradation of such proteins. During autophagy, ubiquitinated proteins are clustered in a p62‐dep...

Descrizione completa

Dettagli Bibliografici
Autori principali:	Zaffagnini, G, Savova, A, Danieli, A, Romanov, J, Tremel, S, Ebner, M, Peterbauer, T, Sztacho, M, Trapannone, R, Tarafder, AK, Sachse, C, Martens, S
Natura:	Journal article
Lingua:	English
Pubblicazione:	EMBO Press 2018

Documenti analoghi

Oligomerization of p62 allows for selection of ubiquitinated cargo and isolation membrane during selective autophagy
di: Bettina Wurzer, et al.
Pubblicazione: (2015-09-01)

Reconstitution defines the roles of p62, NBR1 and TAX1BP1 in ubiquitin condensate formation and autophagy initiation
di: Eleonora Turco, et al.
Pubblicazione: (2021-09-01)

Structural basis of p62/SQSTM1 helical filaments and their role in cellular cargo uptake
di: Arjen J. Jakobi, et al.
Pubblicazione: (2020-01-01)

Mechanism of cargo-directed Atg8 conjugation during selective autophagy
di: Dorotea Fracchiolla, et al.
Pubblicazione: (2016-11-01)

Glycyrol attenuates colon injury via promotion of SQSTM1/p62 ubiquitination and autophagy by inhibiting the ubiquitin-specific protease USP8
di: Shangyun Lu, et al.
Pubblicazione: (2023-04-01)

Filament-filament switching can be regulated by separation between filaments together with cargo motor number.
di: Robert P Erickson, et al.
Pubblicazione: (2013-01-01)

Sequestration of translation initiation factors in p62 condensates
di: Alberto Danieli, et al.
Pubblicazione: (2023-12-01)

Transportation of nanoscale cargoes by myosin propelled actin filaments.
di: Malin Persson, et al.
Pubblicazione: (2013-01-01)

P62/Ubiquitin IHC expression in gastrointestinal carcinomas
di: Amr eMohamed, et al.
Pubblicazione: (2015-03-01)

Ubiquitination in the regulation of autophagy
di: Cen Xueyan, et al.
Pubblicazione: (2023-08-01)

CUL5–ASB6 Complex Promotes p62/SQSTM1 Ubiquitination and Degradation to Regulate Cell Proliferation and Autophagy
di: Liyan Gong, et al.
Pubblicazione: (2021-06-01)

Capturing intermediate filament networks
di: Pierre A Coulombe
Pubblicazione: (2022-04-01)

Special Issue on “Ubiquitin and Autophagy”
di: Taras Y. Nazarko
Pubblicazione: (2021-01-01)

The Roles of Ubiquitin in Mediating Autophagy
di: Zhangyuan Yin, et al.
Pubblicazione: (2020-09-01)

Ubiquitin, Autophagy and Neurodegenerative Diseases
di: Yoshihisa Watanabe, et al.
Pubblicazione: (2020-09-01)

Cargo properties play a critical role in myosin Va-driven cargo transport along actin filaments
di: Arthur J. Michalek, et al.
Pubblicazione: (2022-03-01)

Ubiquitination of alpha-synuclein filaments by Nedd4 ligases.
di: Thomas Mund, et al.
Pubblicazione: (2018-01-01)

The Role of the Ubiquitin-Proteasome System and p62 in the Development of Neurodegenerative Disease
di: Michael G. Paine, et al.
Pubblicazione: (2006-01-01)

Cargo-interacting regions (CIR) of CCPG1 capture ER luminal cargos for reticulophagy
di: Haruka Chino, et al.
Pubblicazione: (2023-12-01)

iNOS Interacts with Autophagy Receptor p62 and is Degraded by Autophagy in Macrophages
di: Jing Wang, et al.
Pubblicazione: (2019-10-01)

Interplay between the Ubiquitin Proteasome System and Ubiquitin-Mediated Autophagy in Plants
di: Tong Su, et al.
Pubblicazione: (2020-10-01)

Correction: Ubiquitination of alpha-synuclein filaments by Nedd4 ligases.
di: PLOS ONE Staff
Pubblicazione: (2018-01-01)

The Roles of Ubiquitin-Binding Protein Shuttles in the Degradative Fate of Ubiquitinated Proteins in the Ubiquitin-Proteasome System and Autophagy
di: Katarzyna Zientara-Rytter, et al.
Pubblicazione: (2019-01-01)

p62 Pathology Model in the Rat Substantia Nigra with Filamentous Inclusions and Progressive Neurodegeneration.
di: Kasey L Jackson, et al.
Pubblicazione: (2017-01-01)

The Autophagy Regulator p62 Controls PTEN-Dependent Ciliogenesis
di: Hyowon Mun, et al.
Pubblicazione: (2020-06-01)

ZZ-dependent regulation of p62/SQSTM1 in autophagy
di: Yi Zhang, et al.
Pubblicazione: (2018-10-01)

Selective Autophagy by Close Encounters of the Ubiquitin Kind
di: Anna Vainshtein, et al.
Pubblicazione: (2020-10-01)

Optineurin: A Coordinator of Membrane-Associated Cargo Trafficking and Autophagy
di: Thomas A. Ryan, et al.
Pubblicazione: (2018-05-01)

Atg45 is an autophagy receptor for glycogen, a non-preferred cargo of bulk autophagy in yeast
di: Takahiro Isoda, et al.
Pubblicazione: (2024-06-01)

The E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresome.
di: Carmela Fusco, et al.
Pubblicazione: (2012-01-01)

Autophagy safeguards conidial environmental persistence in filamentous fungi
di: Jin-Li Ding, et al.
Pubblicazione: (2023-12-01)

The autophagy receptor p62/SQST-1 promotes proteostasis and longevity in C. elegans by inducing autophagy
di: Caroline Kumsta, et al.
Pubblicazione: (2019-12-01)

Roles of autophagy and p62 /SQSTM1 in hepatic ischemia-reperfusion
di: Zhang Haiming, et al.
Pubblicazione: (2021-03-01)

Oxidation of p62 as an evolutionary adaptation to promote autophagy in stress conditions
di: Elsje G. Otten, et al.
Pubblicazione: (2018-03-01)

Evolution of Two Ubiquitin-like System of Autophagy in Orchid
di: Jieyu Wang, et al.
Pubblicazione: (2020-09-01)

The Role of ATG16 in Autophagy and The Ubiquitin Proteasome System
di: Qiuhong Xiong, et al.
Pubblicazione: (2018-12-01)

Autophagy and Ubiquitination in Salmonella Infection and the Related Inflammatory Responses
di: Lidan Wang, et al.
Pubblicazione: (2018-03-01)

Crosstalk Between Mammalian Autophagy and the Ubiquitin-Proteasome System
di: Nur Mehpare Kocaturk, et al.
Pubblicazione: (2018-10-01)

Autophagy is inhibited by ubiquitin ligase activity in the nervous system
di: Oliver Crawley, et al.
Pubblicazione: (2019-11-01)

Capture and transport of rod-shaped cargo via programmable active particles
di: Philipp Stengele, et al.
Pubblicazione: (2023-09-01)