p62 filaments capture and present ubiquitinated cargos for autophagy

p62 filaments capture and present ubiquitinated cargos for autophagy

The removal of misfolded, ubiquitinated proteins is an essential part of the protein quality control. The ubiquitin‐proteasome system (UPS) and autophagy are two interconnected pathways that mediate the degradation of such proteins. During autophagy, ubiquitinated proteins are clustered in a p62‐dep...

Podrobná bibliografie
Hlavní autoři:	Zaffagnini, G, Savova, A, Danieli, A, Romanov, J, Tremel, S, Ebner, M, Peterbauer, T, Sztacho, M, Trapannone, R, Tarafder, AK, Sachse, C, Martens, S
Médium:	Journal article
Jazyk:	English
Vydáno:	EMBO Press 2018

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