In-depth quantitative cardiac proteomics combining electron transfer dissociation and the metalloendopeptidase Lys-N with the SILAC mouse.

In quantitative proteomics stable isotope labeling has progressed from cultured cells toward the total incorporation of labeled atoms or amino acids into whole multicellular organisms. For instance, the recently introduced (13)C(6)-lysine labeled SILAC mouse allows accurate comparison of protein exp...

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Bibliographic Details
Main Authors: Scholten, A, Mohammed, S, Low, T, Zanivan, S, van Veen, T, Delanghe, B, Heck, A
Format: Journal article
Language:English
Published: 2011