N-acyl 'quat' pyrrolidinone auxiliary as a chiral amide equivalent via direct aminolysis
A novel route to chiral amides through the efficient, non-racemising, cleavage of N-acyl side chains from a 'Quat' chiral auxiliary using N-centred nucleophiles is described. The synthetic utility of the procedure is then highlighted by the preparation of a range of succinamide and succini...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2002
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