DNA modification under mild conditions by Suzuki-Miyaura cross-coupling for the generation of functional probes.

Quick and clean: A method for Pd-catalyzed Suzuki-Miyaura cross-coupling to iododeoxyuridine (IdU) in DNA is described. Key to the reactivity is the choice of the ligand and the buffer. A covalent [Pd]-DNA intermediate was isolated and characterized. Photocrosslinking probes were generated to trap p...

সম্পূর্ণ বিবরণ

গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Lercher, L, McGouran, J, Kessler, B, Schofield, C, Davis, B
বিন্যাস: Journal article
ভাষা:English
প্রকাশিত: 2013