Structurally encoded intraclass differences in EphA clusters drive distinct cell responses.

Functional outcomes of ephrin binding to Eph receptors (Ephs) range from cell repulsion to adhesion. Here we used cell collapse and stripe assays, showing contrasting effects of human ephrinA5 binding to EphA2 and EphA4. Despite equivalent ligand binding affinities, EphA4 triggered greater cell coll...

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Bibliographische Detailangaben
Hauptverfasser:	Seiradake, E, Schaupp, A, del Toro Ruiz, D, Kaufmann, R, Mitakidis, N, Harlos, K, Aricescu, A, Klein, R, Jones, E
Format:	Journal article
Sprache:	English
Veröffentlicht:	2013

Structurally encoded intraclass differences in EphA clusters drive distinct cell responses von Seiradake, E, Schaupp, A, Del Toro Ruiz, D, Kaufmann, R, Mitakidis, N, Harlos, K, Aricescu, A, Klein, R, Jones, E

Veröffentlicht 2013

Journal article

Structurally encoded intraclass differences in EphA clusters drive distinct cell responses.

Structurally encoded intraclass differences in EphA clusters drive distinct cell responses von Seiradake, E, Schaupp, A, Del Toro Ruiz, D, Kaufmann, R, Mitakidis, N, Harlos, K, Aricescu, A, Klein, R, Jones, E

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