Role of CD8 in aberrant function of cytotoxic T lymphocytes.
Using H-2Kd-restricted photoprobe-specific cytotoxic T lymphocyte (CTL) clones, which permit assessment of T cell receptor (TCR)-ligand interactions by TCR photoaffinity labeling, we observed that the efficiency of antigen recognition by CTL was critically dependent on the half-life of TCR-ligand co...
Egile Nagusiak: | Kessler, B, Hudrisier, D, Cerottini, J, Luescher, I |
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Formatua: | Journal article |
Hizkuntza: | English |
Argitaratua: |
1997
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Antzeko izenburuak
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Peptide modification or blocking of CD8, resulting in weak TCR signaling, can activate CTL for Fas- but not perforin-dependent cytotoxicity or cytokine production.
nork: Kessler, B, et al.
Argitaratua: (1998) -
The efficiency of antigen recognition by CD8+ CTL clones is determined by the frequency of serial TCR engagement.
nork: Hudrisier, D, et al.
Argitaratua: (1998) -
The efficiency of antigen recognition by CTL is determined by the frequency of serial TCR engagement.
nork: Hudrisier, D, et al.
Argitaratua: (1998) -
Effects of epitope modification on T cell receptor-ligand binding and antigen recognition by seven H-2Kd-restricted cytotoxic T lymphocyte clones specific for a photoreactive peptide derivative.
nork: Kessler, B, et al.
Argitaratua: (1997) -
Antagonism of cytotoxic T-lymphocyte activation by soluble CD8.
nork: Sewell, A, et al.
Argitaratua: (1999)