Role of ITAM signaling module in signal integration

Diverse cell types use a small number of evolutionarily conserved signaling modules to integrate external cues and elicit distinct functions. A question thus arises as to how does a receptor, which contains a single signaling module, produce distinct outcomes to diverse signals, particularly if such...

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Bibliographic Details
Main Authors: Bezbradica, J, Medzhitov, R
Format: Journal article
Language:English
Published: Elsevier 2012