Role of ITAM signaling module in signal integration

Diverse cell types use a small number of evolutionarily conserved signaling modules to integrate external cues and elicit distinct functions. A question thus arises as to how does a receptor, which contains a single signaling module, produce distinct outcomes to diverse signals, particularly if such...

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Detalles Bibliográficos
Autores principales: Bezbradica, J, Medzhitov, R
Formato: Journal article
Lenguaje:English
Publicado: Elsevier 2012