ASYMMETRIC ALDOL AND ALKYLATION REACTIONS MEDIATED BY THE QUAT CHIRAL AUXILIARY (R)-(-)-5-METHYL-3,3-DIMETHYL-2-PYRROLIDINONE

Enolates derived from the N-propionoyl derivative of the "quat" chiral auxiliary (R)-(-)-5-methyl-3,3-dimethyl-2-pyrrolidinone undergo highly stereoselective aldol and alkylation reactions. Removal of the auxiliary has been demonstrated with LiOH, PhCH2OLi, MeOMgBr and LiAlH4 to generate r...

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Váldodahkkit: Davies, S, Doisneau, G, Prodger, J, Sanganee, H
Materiálatiipa: Journal article
Giella:English
Almmustuhtton: 1994