CDK9 and PP2A regulate RNA polymerase II transcription termination and coupled RNA maturation

CDK9 is a kinase critical for the productive transcription of protein-coding genes by RNA polymerase II (pol II). As part of P-TEFb, CDK9 phosphorylates the carboxyl-terminal domain (CTD) of pol II and elongation factors, which allows pol II to elongate past the early elongation checkpoint (EEC) enc...

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Bibliographic Details
Main Authors: Tellier, M, Zaborowska, J, Neve, J, Nojima, T, Hester, S, Fournier, M, Furger, A, Murphy, S
Format: Journal article
Language:English
Published: EMBO Press 2022