CDK9 and PP2A regulate RNA polymerase II transcription termination and coupled RNA maturation
CDK9 is a kinase critical for the productive transcription of protein-coding genes by RNA polymerase II (pol II). As part of P-TEFb, CDK9 phosphorylates the carboxyl-terminal domain (CTD) of pol II and elongation factors, which allows pol II to elongate past the early elongation checkpoint (EEC) enc...
Main Authors: | Tellier, M, Zaborowska, J, Neve, J, Nojima, T, Hester, S, Fournier, M, Furger, A, Murphy, S |
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Format: | Journal article |
Language: | English |
Published: |
EMBO Press
2022
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