Transcriptional regulation of endothelial KLF2 in vascular development
The development of a functional vascular system is critically dependent on shear stress, a hemodynamic force exerted onto the vascular endothelium by flowing blood. Krüppel-like factor 2 (KLF2) is the central transcriptional regulator of the endothelial shear stress response, yet the mechanisms by w...
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Format: | Thesis |
Language: | English |
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2022
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