Transcriptional regulation of endothelial KLF2 in vascular development

The development of a functional vascular system is critically dependent on shear stress, a hemodynamic force exerted onto the vascular endothelium by flowing blood. Krüppel-like factor 2 (KLF2) is the central transcriptional regulator of the endothelial shear stress response, yet the mechanisms by w...

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Bibliographic Details
Main Author: Fleisinger, L
Other Authors: de Val, S
Format: Thesis
Language:English
Published: 2022
Subjects: