Cytomegalovirus (CMV) epitope-specific CD4(+) T cells are inflated in HIV(+) CMV(+) subjects

Cytomegalovirus (CMV) epitope-specific CD4(+) T cells are inflated in HIV(+) CMV(+) subjects

Select CMV epitopes drive life-long CD8(+) T cell memory inflation, but the extent of CD4 memory inflation is poorly studied. CD4(+) T cells specific for human CMV (HCMV) are elevated in HIV(+) HCMV(+) subjects. To determine whether HCMV epitope-specific CD4(+) T cell memory inflation occurs during...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Abana, CO, Pilkinton, MA, Gaudieri, S, Chopra, A, McDonnell, WJ, Wanjalla, C, Barnett, L, Gangula, R, Hager, C, Jung, DK, Engelhardt, BG, Jagasia, MH, Klenerman, P, Phillips, EJ, Koelle, DM, Kalams, SA, Mallal, SA
Format: Journal article
Sprache:English
Veröffentlicht: American Association of Immunologists 2017

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