Bayesian methods for meta-analysis of causal relationships estimated using genetic instrumental variables.

Genetic markers can be used as instrumental variables, in an analogous way to randomization in a clinical trial, to estimate the causal relationship between a phenotype and an outcome variable. Our purpose is to extend the existing methods for such Mendelian randomization studies to the context of m...

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Bibliographic Details
Main Authors:	Burgess, S, Thompson, S, Andrews, G, Samani, N, Hall, A, Whincup, P, Morris, R, Lawlor, D, Davey Smith, G, Timpson, N, Ebrahim, S, Ben-Shlomo, Y, Brown, M, Ricketts, S, Sandhu, M, Reiner, A, Psaty, B, Lange, L, Cushman, M, Hung, J, Thompson, P
Format:	Journal article
Language:	English
Published:	2010

Bayesian methods for meta-analysis of causal relationships estimated using genetic instrumental variables.

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