Haptoglobin and sickle cell polymorphisms and risk of active trachoma in Gambian children

BACKGROUND: Susceptibility and resistance to trachoma, the leading infectious cause of blindness, have been associated with a range of host genetic factors. In vitro studies of the causative organism, Chlamydia trachomatis, demonstrate that iron availability regulates its growth, suggesting that hos...

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Bibliographic Details
Main Authors: Savy, M, Hennig, B, Doherty, C, Fulford, A, Bailey, R, Holland, M, Sirugo, G, Rockett, K, Kwiatkowski, D, Prentice, A, Cox, SE
Format: Journal article
Language:English
Published: Public Library of Science 2010