Molecular flexibility of DNA as a key determinant of RAD51 recruitment
The timely activation of homologous recombination is essential for the maintenance of genome stability, in which the RAD51 recombinase plays a central role. Biochemically, human RAD51 polymerises faster on single‐stranded DNA (ssDNA) compared to double‐stranded DNA (dsDNA), raising a key conceptual...
Main Authors: | , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
EMBO Press
2020
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