Genetically engineered metal ion binding sites on the outside of a Channel's transmembrane beta-barrel.

We are exploring the ability of genetically engineered versions of the Staphylococcus aureus alpha-hemolysin (alphaHL) ion channel to serve as rationally designed sensor components for analytes including divalent cations. We show here that neither the hemolytic activity nor the single channel curren...

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Príomhchruthaitheoirí: Kasianowicz, J, Burden, D, Han, L, Cheley, S, Bayley, H
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: 1999