Combinatorial HLA-peptide bead libraries for high throughput identification of CD8+ T cell specificity

Comprehensive antigenic characterization of a T cell population of unknown specificity is challenging. Existing MHC class I expression systems are limited by the practical difficulty of probing cell populations with an MHC class I peptide library and the cross-reactivity of T cells that are able to...

Полное описание

Библиографические подробности
Главные авторы: Pan, X, Huang, L, Dong, T, Peng, Y, Cerundolo, V, McGowan, S, Ogg, G
Формат: Journal article
Язык:English
Опубликовано: 2014