DNA damage remodels the MITF interactome to increase melanoma genomic instability

DNA damage remodels the MITF interactome to increase melanoma genomic instability

Since genome instability can drive cancer initiation and progression, cells have evolved highly effective and ubiquitous DNA damage response (DDR) programs. However, some cells (for example, in skin) are normally exposed to high levels of DNA-damaging agents. Whether such high-risk cells possess lin...

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Autors principals: Binet, R, Lambert, J-P, Tomkova, M, Tischfield, S, Baggiolini, A, Picaud, S, Sarkar, S, Louphrasitthiphol, P, Dias, D, Carreira, S, Humphrey, TC, Fillipakopoulos, P, White, R, Goding, CR
Format: Journal article
Idioma:English
Publicat: Cold Spring Harbor Laboratory Press 2024

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