DNA damage remodels the MITF interactome to increase melanoma genomic instability

Since genome instability can drive cancer initiation and progression, cells have evolved highly effective and ubiquitous DNA damage response (DDR) programs. However, some cells (for example, in skin) are normally exposed to high levels of DNA-damaging agents. Whether such high-risk cells possess lin...

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Hlavní autoři: Binet, R, Lambert, J-P, Tomkova, M, Tischfield, S, Baggiolini, A, Picaud, S, Sarkar, S, Louphrasitthiphol, P, Dias, D, Carreira, S, Humphrey, TC, Fillipakopoulos, P, White, R, Goding, CR
Médium: Journal article
Jazyk:English
Vydáno: Cold Spring Harbor Laboratory Press 2024