Improvement in mood and fatigue after dehydroepiandrosterone replacement in Addison's disease in a randomized, double blind trial.

Dehydroepiandrosterone (DHEA) and DHEA sulfate (DHEAS) are adrenal precursors of steroid biosynthesis and centrally acting neurosteroids. Glucocorticoid and mineralocorticoid deficiencies in Addison's disease require life-long hormone replacement, but the associated failure of DHEA synthesis is...

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Bibliographic Details
Main Authors: Hunt, P, Gurnell, E, Huppert, F, Richards, C, Prevost, A, Wass, J, Herbert, J, Chatterjee, V
Format: Journal article
Language:English
Published: 2000