Immunological intervention reveals reciprocal roles for tumor necrosis factor-alpha and interleukin-10 in rheumatoid arthritis and systemic lupus erythematosus.

In RA (and in collagen-induced arthritis in DBA/l mice) experimental evidence has convincingly demonstrated the therapeutic benefit of anti-TNF-α antibodies, whereas anti-TNF-α also induces lupus-associated DNA antibodies in a minority of presumably genetically susceptible individuals, and accelerat...

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Những tác giả chính: Maini, R, Elliott, M, Charles, P, Feldmann, M
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: Springer-Verlag 1994