Neurodegeneration in SCA14 is associated with increased PKCγ kinase activity, mislocalization and aggregation
Spinocerebellar ataxia type 14 (SCA14) is a subtype of the autosomal dominant cerebellar ataxias that is characterized by slowly progressive cerebellar dysfunction and neurodegeneration. SCA14 is caused by mutations in the PRKCG gene, encoding protein kinase C gamma (PKCγ). Despite the identificatio...
| Main Authors: | , , , , , , , , , |
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| Format: | Journal article |
| Published: |
BioMed Central
2018
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