Ultra acidic strong cation exchange enabling the efficient enrichment of basic phosphopeptides.

We present a straightforward method to enrich phosphopeptides with multiple basic residues, an under-represented class in common enrichment strategies. Our method is based on a two-dimensional strong cation exchange (SCX) strategy, operating at two different acidic pHs, enabling both separation and...

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Váldodahkkit: Hennrich, M, van den Toorn, H, Groenewold, V, Heck, A, Mohammed, S
Materiálatiipa: Journal article
Giella:English
Almmustuhtton: 2012