Serine ADP-Ribosylation Depends on HPF1

ADP-ribosylation (ADPr) regulates important patho-physiological processes through its attachment to different amino acids in proteins. Recently, by precision mapping on all possible amino acid residues, we identified histone serine ADPr marks in the DNA damage response. However, the biochemical basi...

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Bibliographic Details
Main Authors: Bonfiglio, J, Fontana, P, Zhang, Q, Colby, T, Gibbs-Seymour, I, Atanassov, I, Bartlett, E, Zaja, R, Ahel, I, Matic, I
Format: Journal article
Language:English
Published: Cell Press 2017