Importance of antigen specificity for complement-mediated lysis by monoclonal antibodies.

Lysis of human lymphocytes by autologous complement had been studied using a range of monoclonal antibodies against different antigens. Antigen specificity (and not antibody isotype) was the most important factor which influenced cell lysis and this could not be accounted for merely by differences i...

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Bibliographic Details
Main Authors: Bindon, C, Hale, G, Waldmann, H
Format: Journal article
Language:English
Published: 1988