Dihydrofolate reductase protects endothelial nitric oxide synthase from uncoupling in tetrahydrobiopterin deficiency

Eitemau Tebyg

• Dihydrofolate reductase protects endothelial nitric oxide synthase from uncoupling in tetrahydrobiopterin deficiency.
  gan: Crabtree, M, et al.
  Cyhoeddwyd: (2011)
• Integrated redox sensor and effector functions for tetrahydrobiopterin- and glutathionylation-dependent endothelial nitric-oxide synthase uncoupling.
  gan: Crabtree, M, et al.
  Cyhoeddwyd: (2013)
• Critical role for tetrahydrobiopterin recycling by dihydrofolate reductase in regulation of endothelial nitric-oxide synthase coupling: relative importance of the de novo biopterin synthesis versus salvage pathways.
  gan: Crabtree, M, et al.
  Cyhoeddwyd: (2009)
• Endothelial tetrahydrobiopterin deficiency accelerates atherosclerotic progression by nitric oxide synthase uncoupling
  gan: Khoo, J, et al.
  Cyhoeddwyd: (2005)
• Dihydrofolate reductase is required to maintain endothelial nitric oxide synthase coupling in vivo: Insights from methotrexate-treated BH4 deficient and GTPCH overexpressing mice
  gan: Crabtree, M, et al.
  Cyhoeddwyd: (2010)