Fine mapping of the MHC Class III region demonstrates association of AIF1 and rheumatoid arthritis.

OBJECTIVES: The heritability of RA has been estimated to be approximately 55%, of which the MHC contributes about one-third. HLA-DRB1 alleles are strongly associated with RA, but it is likely that significant non-DRB1 MHC genetic susceptibility factors are involved. Previously, we identified two th...

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Bibliografische gegevens
Hoofdauteurs: Harney, S, Vilariño-Güell, C, Adamopoulos, I, Sims, A, Lawrence, R, Cardon, L, Newton, J, Meisel, C, Pointon, J, Darke, C, Athanasou, N, Wordsworth, B, Brown, M
Formaat: Journal article
Taal:English
Gepubliceerd in: 2008