Tryptophan 2,3-dioxygenase expression identified in human hepatocellular carcinoma cells and in intratumoral pericytes of most cancers

Tryptophan catabolism is used by tumors to resist immune attack. It can be catalyzed by indoleamine 2,3-dioxygenase (IDO1) and tryptophan 2,3-dioxygenase (TDO). IDO1 is frequently expressed in tumors and has been widely studied as a potential therapeutic target to reduce resistance to cancer immunot...

詳細記述

書誌詳細
主要な著者: Hoffmann, D, Dvorakova, T, Stroobant, V, Bouzin, C, Daumerie, A, Solvay, M, Klaessens, S, Letellier, M-C, Renauld, J-C, van Baren, N, Lelotte, J, Marbaix, E, Van den Eynde, BJ
フォーマット: Journal article
言語:English
出版事項: American Association for Cancer Research 2019