Choosing the target difference ('effect size') for a randomised controlled trial - DELTA(2) guidance protocol.

<p>BACKGROUND: A key step in the design of a randomised controlled trial (RCT) is the estimation of the number of participants needed. By far the most common approach is to specify a target difference and then estimate the corresponding sample size; this sample size is chosen to provide reassu...

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Main Authors:	Cook, JA, Julious, SA, Sones, W, Rothwell, JC, Ramsay, CR, Hampson, LV, Emsley, R, Walters, SJ, Hewitt, C, Bland, M, Fergusson, DA, Berlin, JA, Altman, D, Vale, LD
Format:	Journal article
Sprog:	English
Udgivet:	BioMed Central 2017

Choosing the target difference ('effect size') for a randomised controlled trial - DELTA(2) guidance protocol.

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