Human endogenous retrovirus (HERV) expression is not induced by treatment with the histone deacetylase (HDAC) inhibitors in cellular models of HIV-1 latency

Background While antiretroviral therapies have improved life expectancy and reduced viral loads in HIV-1-positive individuals, the cessation of treatment results in a rebound of viral replication. This suggests that a reservoir of latently-infected cells remains within these patients, the identity...

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Bibliographic Details
Main Authors: Hurst, T, Pace, M, Katzourakis, A, Phillips, R, Klenerman, P, Frater, J, Magiorkinis, G
Format: Journal article
Published: BioMed Central 2016