Human endogenous retrovirus (HERV) expression is not induced by treatment with the histone deacetylase (HDAC) inhibitors in cellular models of HIV-1 latency
Background While antiretroviral therapies have improved life expectancy and reduced viral loads in HIV-1-positive individuals, the cessation of treatment results in a rebound of viral replication. This suggests that a reservoir of latently-infected cells remains within these patients, the identity...
Main Authors: | Hurst, T, Pace, M, Katzourakis, A, Phillips, R, Klenerman, P, Frater, J, Magiorkinis, G |
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Format: | Journal article |
Published: |
BioMed Central
2016
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