DNA-guided DNA interference by a prokaryotic Argonaute.

RNA interference is widely distributed in eukaryotes and has a variety of functions, including antiviral defence and gene regulation. All RNA interference pathways use small single-stranded RNA (ssRNA) molecules that guide proteins of the Argonaute (Ago) family to complementary ssRNA targets: RNA-gu...

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Bibliographic Details
Main Authors: Swarts, D, Jore, M, Westra, E, Zhu, Y, Janssen, J, Snijders, A, Wang, Y, Patel, D, Berenguer, J, Brouns, S, van der Oost, J
Format: Journal article
Language:English
Published: 2014