Early acquisition of cytolytic function and transcriptional changes in a primary CD8+ T-cell response in vivo.

Early acquisition of cytolytic function and transcriptional changes in a primary CD8+ T-cell response in vivo.

Functional studies show that programming of CD8+ T cells occurs early after initial antigen encounter within as little as 2 hours. To define the molecular basis of these events, we transferred TCR transgenic T cells from F5 Rag-/- mice into naive recipients and stimulated them with recombinant vacci...

תיאור מלא

מידע ביבליוגרפי
Main Authors:	Chiu, C, Heaps, A, Cerundolo, V, Mcmichael, A, Bangham, C, Callan, M
פורמט:	Journal article
שפה:	English
יצא לאור:	2007

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