Formation of the sinus node head and differentiation of sinus node myocardium are independently regulated by Tbx18 and Tbx3.

The sinus node (or sinoatrial node [SAN]), the pacemaker of the heart, is a functionally and structurally heterogeneous tissue, which consists of a large "head" within the right caval vein myocardium and a "tail" along the terminal crest. Here, we investigated its cellular origin...

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Bibliographic Details
Main Authors: Wiese, C, Grieskamp, T, Airik, R, Mommersteeg, M, Gardiwal, A, de Gier-de Vries, C, Schuster-Gossler, K, Moorman, A, Kispert, A, Christoffels, V
Format: Journal article
Language:English
Published: 2009