Two types of BCR interactions are positively selected during leukemia development in the Eμ-TCL1 transgenic mouse model of CLL.

Two types of BCR interactions are positively selected during leukemia development in the Eμ-TCL1 transgenic mouse model of CLL.

Chronic lymphocytic leukemia (CLL) is a common B-cell malignancy characterized by a highly variable course and outcome. The disease is believed to be driven by B-cell receptor (BCR) signals generated by external antigens and/or cell-autonomous BCR interactions, but direct in vivo evidence for this i...

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Detalles Bibliográficos
Main Authors: Iacovelli, S, Hug, E, Bennardo, S, Duehren-von Minden, M, Gobessi, S, Rinaldi, A, Suljagic, M, Bilbao, D, Bolasco, G, Eckl-Dorna, J, Niederberger, V, Autore, F, Sica, S, Laurenti, L, Wang, H, Cornall, R, Clarke, S, Croce, C, Bertoni, F, Jumaa, H, Efremov, D
Formato: Journal article
Idioma:English
Publicado: 2015

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