Association between a selective 5-HT4 receptor agonist and incidence of major depressive disorder: emulated target trial
<p><b>Background</b></p> The serotonin 4 receptor (5-HT4R) is a promising target for the treatment of depression. Highly selective 5-HT4R agonists, such as prucalopride, have antidepressant-like and procognitive effects in preclinical models, but their clinical effects are no...
Main Authors: | de Cates, AN, Harmer, CJ, Harrison, PJ, Cowen, PJ, Emmanuel, A, Travis, S, Murphy, SE, Taquet, M |
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Format: | Journal article |
Language: | English |
Published: |
Cambridge University Press
2024
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