Engineered α-hemolysin pores with chemically and genetically-fused functional proteins

<p>Protein engineering could be used to bring two proteins together, which don't normally interact, in an oriented configuration. Using computer modelling and experimental work involving mutagenesis, a new dimer complex, (α7)2, was engineered with two α-hemolysin (αHL) heptamers (α7) unit...

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Bibliographic Details
Main Author: Mantri, S
Other Authors: Bayley, H
Format: Thesis
Language:English
Published: 2013
Subjects: