HIV-1 gp41 envelope IgA is frequently elicited after transmission but has an initial short response half-life.
Prevention of HIV-1 transmission at mucosal surfaces will likely require durable pre-existing mucosal anti-HIV-1 antibodies (Abs). Defining the ontogeny, specificities and potentially protective nature of the initial mucosal virus-specific B-cell response will be critical for understanding how to in...
Autori principali: | , , , , , , , , , , , , |
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Natura: | Journal article |
Lingua: | English |
Pubblicazione: |
2013
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