Fine mapping of candidate effector genes for heart rate
An elevated resting heart rate (RHR) is associated with increased cardiovascular mortality. Genome-wide association studies (GWAS) have identified > 350 loci. Uniquely, in this study we applied genetic fine-mapping leveraging tissue specific chromatin segmentation and colocalization analyses to i...
Main Authors: | , , , , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
Springer
2024
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