Reduction of cPLA2alpha overexpression: an efficient anti-inflammatory therapy for collagen-induced arthritis.

Reduction of cPLA2alpha overexpression: an efficient anti-inflammatory therapy for collagen-induced arthritis.

Cytosolic phospholipase A2alpha (cPLA2) plays an important role in the development of several inflammatory diseases. The aim of the present study is to determine whether inhibition of cPLA2 expression, using specific antisense oligonucleotides against cPLA2 (antisense), is efficient in reducing infl...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Raichel, L, Berger, S, Hadad, N, Kachko, L, Karter, M, Szaingurten-Solodkin, I, Williams, R, Feldmann, M, Levy, R
التنسيق:	Journal article
اللغة:	English
منشور في:	2008

مواد مشابهة

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Therapeutic actions of cyclosporine and anti-tumor necrosis factor alpha in collagen-induced arthritis and the effect of combination therapy.
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