Targeting the type 1 insulin-like growth factor receptor as a treatment for cancer.
BACKGROUND: The type 1 insulin-like growth factor receptor (IGF1R) plays a critical role in transformation, invasion and apoptosis protection, and is an attractive cancer treatment target. OBJECTIVE: To review IGF1R antibodies and kinase inhibitors that are in preclinical and clinical development, a...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2008
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