Bifunctional nanoarrays for probing the immune response at the single-molecule level.

Bifunctional nanoarrays were created to simulate the immunological synapse and probe the T-cell immune response at the single-molecule level. Sub-5 nm AuPd nanodot arrays were fabricated using both e-beam and nanoimprint lithography. The nanoarrays were then functionalized by two costimulatory molec...

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Bibliographic Details
Main Authors: Cai, H, Depoil, D, Palma, M, Sheetz, M, Dustin, M, Wind, S
Format: Journal article
Language:English
Published: 2013