Mitochondrial damage contributes to Pseudomonas aeruginosa activation of the inflammasome and is downregulated by autophagy.

Mitochondrial damage contributes to Pseudomonas aeruginosa activation of the inflammasome and is downregulated by autophagy.

The nucleotide-binding domain, leucine-rich repeat containing family caspase recruitment domain containing 4 (NLRC4) inflammasome can be activated by pathogenic bacteria via products translocated through the microbial type III secretion apparatus (T3SS). Recent work has shown that activation of the...

Полное описание

Библиографические подробности
Главные авторы:	Jabir, MS, Hopkins, L, Ritchie, N, Ullah, I, Bayes, H, Li, D, Tourlomousis, P, Lupton, A, Puleston, D, Simon, A, Bryant, C, Evans, T
Формат:	Journal article
Язык:	English
Опубликовано:	2015

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